SACHA (Secured Access to innovative medicines for CHildren, adolescents and young adults with cAncer) is an international observational registry coordinated by Gustave Roussy. It aims to secure access to innovative anticancer medicines for children, adolescents and young adults (AYA) outside of clinical trials, while collecting real-world evidence (RWE) of safety and efficacy to inform future research and regulatory decisions.

Launched in France in 2020, SACHA expanded to multiple countries from 2023 onwards thanks to the support of Fight Kids Cancer, and now brings together pediatric oncology centres committed to securing access to innovation.